Overview Aging has a biology, and this biology drives age-related diseases (Geroscience). We at Einstein have demonstrated that the biology of aging can be targeted in experimental models to delay, stop, and in some examples, reverse manifestations of aging. Our overarching Mission is to make scientific discoveries in geroscience, leveraging on the expertise in our center in studying and targeting the pillars of aging, and to confirm their relevance of new findings to human aging through the unique Gero-human resource created in our center and to translate interventions proven relevant for human to drug discovery efforts. Centers of Excellence The institute for Aging Research is the home of two aging centers of international recognition. The Nathan Shock Center of Excellence, focused on the study of the biology of aging and the Einstein Paul F. Glenn Center solely dedicate to understanding the biology behind human Aging. Learn More Nathan Shock Center of Excellence LEARN MORE The Paul F. Glenn Center for Biology of Human Aging LEARN MORE Research Integrative Physiology Dietary strategies to delay aging Metabolism targeting to delay aging Cell autonomous and non-autonomous aging CNS control of metabolism and aging Cell Biology of Aging Proteostasis DNA repair Response to Stress Inflammaging Stem Cells Genetics of Aging Human Longevity Comparative genomics of longevity Translational Geroscience TAME Human Longevity Studies Clinical Geriatrics Training Einstein's Institute for Aging Research is committed to the development the next generation scientists in the biology of aging. Training programs are available for graduate and postdoctoral candidates. Learn More Multimedia 2nd Annual Longevity Studies Symposium More Videos Highlights See All Publications See More Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy Next questions in autophagy Autophagy gene expression in skeletal muscle of older individuals is associated with physical performance, muscle volume and mitochondrial function in the study of muscle, mobility and aging (SOMMA) Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology Somatic mutations in aging and disease