Anthony-Gonda K, Bardhi A, Ray A, Flerin N, Li M, Chen W, Ochsenbauer C, Kappes JC, Krueger W, Worden A, Schneider D, Zhu Z, Orentas R, Dimitrov D, Goldstein H, Dropulić B. Multi-specific anti-HIV duoCAR-T cells display broad in vitro antiviral activity and potent in vivo elimination of HIV-infected cells. Science Translational Med. 2019:11:pii: eaav5685. doi: 10.1126/scitranslmed.aav5685. PubMed PMID: 31391322.
Flerin NC, Bardhi A, Zheng JH, Korom M, Folkvord J, Kovacs C, Benko E, Truong R, Mota T, Connick E, Jones RB, Lynch RM, Goldstein H. Establishment of A Novel Humanized Mouse Model To Investigate In Vivo Activation and Depletion of Patient-Derived HIV Latent Reservoirs. J. Virology 2019:93:pii: e02051-18. doi: 10.1128/JVI.02051-18. PubMed PMID: 30626677. PMCID: PMC6401459.
Bardhi A, Wu Y, Chen W, Zhu Z, Zheng JH, Wong H, Jeng E, Jones J, Ochsenbauer C, Kappes JC, Dimitrov DS, Ying T, Goldstein H. Potent in vivo NK cell-mediated elimination of HIV-1-Infected cells mobilized by a gp120-bispecific and hexavalent broadly neutralizing fusion protein. J. Virology 2017:91:pii: 00937-17. doi: 10.1128/JVI.00937-17. PubMed PMID: 28794022. PMCID: PMC5625480.
Flerin NC, Chen H, Glover TD, Lamothe PA, Zheng JH, Fang JW, Ndhlovu ZM, Newell EW, Davis MM, Walker BD, Goldstein H. T-Cell Receptor (TCR) Clonotype-Specific Differences in Inhibitory Activity of HIV-1 Cytotoxic T-Cell Clones Is Not Mediated by TCR Alone. J. Virology 2017;91:e02412-16. doi: 10.1128/JVI.02412-16.
Thomas T, Seay K, Zheng JH, Zhang C, Ochsenbauer C, Kappes JC, Goldstein H. High-Throughput Humanized Mouse Models for Evaluation of HIV-1 Therapeutics and Pathogenesis. Methods Mol Biol. 2016;1354:221-35. doi: 10.1007/978-1-4939-3046-3_15
Seay K, Khajoueinejad N, Zheng JH, Kiser P, Ochsenbauer C, Kappes JC, Herold B, Goldstein H. The vaginal acquisition and dissemination of HIV-1 infection in a novel transgenic mouse model is facilitated by coinfection with HSV-2 and is inhibited by microbicide treatment. J. Virology 2015;89:9559-9570. doi: 10.1128/JVI.01326-15.
Seay K, Church C, Zheng JH, Deneroff K, Ochsenbauer C, Kappes JC, Liu B, Jeng EK, Wong HC, Goldstein H. In vivo activation of human NK Cells by treatment with an Interleukin-15 superagonist potently inhibits acute in vivo HIV-1 infection in humanized mice. J. Virology 2015;89:6264-6274. doi: 10.1128/JVI.00563-15.
Costantini LM, Irvin SC, Kennedy SC, Guo F, Goldstein H, Herold BC, Snapp EL. Engineering and exploitation of a fluorescent HIV-1 gp120 for live cell CD4 binding assays. Virology. 2015 476:240-248. doi: 10.1016/j.virol.2014.12.019.
Nixon B, Fakioglu E, Stefanidou M, Wang Y, Dutta M, Goldstein H, Herold BC. Genital herpes simplex virus type 2 infection in humanized HIV-transgenic mice triggers HIV shedding and is associated with greater neurological disease. J Infect Dis. 2014;209:510-22. doi: 10.1093/infdis/jit472.
Seay K, Qi X, Zheng JH, Zhang C, Chen K, Dutta M, Deneroff K, Ochsenbauer C, Kappes JC, Littman DR, Goldstein H. Mice transgenic for CD4-specific human CD4, CCR5 and cyclin T1 expression: a new model for investigating HIV-1 transmission and treatment efficacy. PLoS ONE. 2013;8(5):e63537. doi: 10.1371/journal.pone.0063537.