Hepatic Imaging and Cell Structure

Overview

The Imaging and Cell Structure Core provides expertise in morphology and microscopy of liver tissue and liver cell cultures, including consultation and interpretation of data for Einstein investigators. The core facilitates access to state-of-the-art microscopes and provides training and instruction in a broad range of tissue- and cell-based methods. In addition, advice is provided on which microscopes and methods are appropriate for imaging normal and pathologic liver in real and fixed times and at different levels of tissue and cell organization (i.e., from overall topography to subcellular structures and molecular composition).

Services

Histology, histochemistry, enzyme- and immunocytochemistry (fluorescence, gold, peroxidase) by widefield light microscopy
Fluorescent dye antibodies, cell dyes, and fluorescent protein plasmids
Fluorescence immunochemistry by confocal microscopy
Live cell imaging by widefield, confocal, and deconvolution microscopy
Cell topography and cell ultrastructure by scanning and transmission electron microscopy, including cryo- and immuno-electron microscopy
Laser capture microdissection microscopy