How Do Children Fight Off the Coronavirus?

Betsy Herold, M.D., describes her new research that may help explain why the novel coronavirus affects children less severely than adults. Dr. Herold is chief of pediatric infectious diseases and vice chair for pediatrics research at Einstein and Montefiore and the Harold and Muriel Block Chair in Pediatrics.

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Science News interviews Betsy Herold, M.D., about her new research with William Jacobs, Jr., Ph.D., on an experimental herpes vaccine. Dr. Herold explains that their novel approach was to silence the loud, or dominant, surface protein on the virus in order to use the other proteins to trigger an effective immune response. Dr. Herold holds the Harold and Muriel Block Chair in Pediatrics at Einstein and is the chief of the division of pediatric infectious diseases at the Children's Hospital at Montefiore and Einstein. Dr. Jacobs is a Howard Hughes Medical Institute Investigator and the Leo and Julia Forchheimer Chair in Microbiology & Immunology at Einstein.