COVID-19: Read the latest research news and education updates

Einstein Community: Review policies & guidelines, access self-check app, and view dashboard.

  • Library
  • Intranet
Albert Einstein College of Medicine
  • About
  • Education
  • Research
  • Departments & Centers
Giving
Search
Menu
Montefiore Health System
  • Faculty Directory
  • Research Connections
  • Faculty Directory
  • Research Connections
Information For
  • Alumni
  • Donors
  • Faculty
  • Postdocs
  • Students (Prospective, Current)
  • Visitors
Quick Links
  • About
  • Administration
  • Departments & Centers
  • Directory
  • Education & Admissions
  • Events
  • Find Faculty
  • Giving
  • Health
  • Intranet
  • Library
  • Research
  • Webmail
News & Media
  • Newsroom
  • Blog
  • Einstein in the News
  • Expert List for Media
  • Features
  • Magazine
  • Multimedia
  • News Releases
  • Research Briefs
  • Social Media Hub

Faculty Profile

  • Home
  • Faculty Directory
  • Joshua D. Nosanchuk, M.D.

Joshua D. Nosanchuk, M.D.

Joshua D. Nosanchuk

Professor, Department of Medicine (Infectious Diseases)

Professor, Department of Microbiology & Immunology

Senior Associate Dean for Medical Education

Area of Research: medical education; assessment; fungal pathogenesis; host-pathogen biology; regenerative medicine; innovative therapeutics

Contact Information

718.430.3371718.430.8825

Albert Einstein College of Medicine
Jack and Pearl Resnick Campus

1300 Morris Park Avenue
Belfer Building, Room 211
Bronx, NY 10461

Research ProfilesPubMed Portal

Is this your profile? Edit profile

Professional Interests

Medical Education: As Senior Associate Dean for Medical Education, I oversee all aspects of the educational experience of Einstein’s diverse and exceptional medical students. We are continuously striving to innovate our approach to medical education, building upon Einstein’s outstanding basic and translational scientific opportunities, our commitment to community-based programming and team-based active learning, and our rigorous clinical skills experiences. Infused with a humanistic approach to medicine, in which medical students enagage in advocacy for their patients, Einstein’s medical training continues to reflect the institution’s mission of promoting social justice and delivering quality care to all. 

Basic Science Laboratory: There are two main areas of research in the Nosanchuk laboratory: fungal pathogenesis and innovative therapeutic development. 

Fungal diseases are a major global health threat, resulting in over 1.5 million deaths annually. A dramatic rise in fungal disease incidence over the past few decades is directly associated with the growing numbers of immunocompromised individuals, particularly patients receiving chemo- or immuno-therapy, recovering from invasive surgery, or individuals with HIV/AIDS. Despite the increased prevalence of mycotic diseases, there remains an enormous gap in knowledge and our current therapeutic armamentarium all too often fails to eradicate these insidious pathogens. The Nosanchuk laboratory is investigating the pathogenesis of human pathogenic fungi, especially Histoplasma capsulatum, Candida parapsilosis, Candida auris and Cryptococcus neoformans. In particular, we are focusing on 1) how antibody can modify disease outcomes and 2) the role of melanin production on pathogenesis. We are also working on deciphering the impact of extracellular release of vesicles from fungi, which contain numerous products associated with virulence.

A second focus area of the laboratory is on innovative approaches to combat 1) fungal infections and 2) wound healing, especially leveraging the delivery of compounds via antibody or nanoparticles. With antibodies, we are using the approach of radioimmunotherapy (labeling antibody with a radionuclide). For fungi, we have identified cell surface antigens that are conserved on diverse fungi in order to develop a “pan-antifungal” therapeutic. In more advanced development, we are using antibodies to melanin for the treatment of melanoma. In collaboration with the laboratory of Dr. David Sharp (Physiology & Biophysics), we are targeting microtubule severing enzymes as a mechanism for tightly regulating cell migration in order to enhance tissue regeneration. In collaboration with Dr. Joel Friedman (Medicine and Physiology & Biophysics) we are exploring diverse applications of a novel, simple and inexpensive nanoparticle platform for drug delivery. We are exploring the therapeutic potential of nitric oxide delivered in sustained release by the nanoparticles for accelerating wound healing as well as for the treatment of diverse infectious diseases, including bacterial and fungal diseases.

Nosanchuk Laboratory Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=nosanchuk+j

Related News

More News

  • Einstein Students Join COVID-19 Vaccination Effort
    Feature
    Einstein Students Join COVID-19 Vaccination Effort

    Feb 03, 2021

  • Einstein Welcomes New Class of Medical Students and Introduces Innovative Curriculum Changes
    News Release
    Einstein Welcomes New Class of Medical Students and Introduces Innovative Curriculum Changes

    Sep 08, 2020

  • Albert Einstein College of Medicine Holds Early Graduation to Help Confront COVID-19 Pandemic
    News Release
    Albert Einstein College of Medicine Holds Early Graduation to Help Confront COVID-19 Pandemic

    Apr 17, 2020

  • Fourth-Year Medical Students Join the Fight Against COVID-19
    Feature
    Fourth-Year Medical Students Join the Fight Against COVID-19

    Apr 07, 2020

In the News

  • Back to Medical School During COVID-19

    AAMC News - August 11, 2020

    Joshua Nosanchuk, M.D., describes how Einstein medical students are helping to revise select courses in response to the COVID-19 pandemic. Dr. Nosanchuk is senior associate dean for medical education and professor of medicine and of microbiology & immunology at Einstein.

Albert Einstein College of Medicine
Jack and Pearl Resnick Campus
1300 Morris Park Avenue
Bronx, NY 10461
718.430.2000
Affiliated With
Montefiore Health
Yeshiva University
  • About Einstein
    • History
    • Dean's Page
    Administration
    • Administrative Departments
    Alumni
  • Careers
    Centers (Research)
    Contact Us
    Departments
    Donors
    • Giving to Einstein
  • Education
    • Graduate Medical Education (G.M.E.)
    • Graduate Program (Ph.D.)
    • Master of Science in Bioethics (M.B.E.)
    • Master of Science in Clinical Research Methods (M.S.)
    • Medical Program (M.D.)
    • MSTP Program (M.D. - Ph.D.)
  • Einstein Senate
    Faculty Directory
    Health
    • Affiliated Institutions
    • Clinical Programs
    • Global Health
    • E-M Partnership
    INTRANET
    Library
    Luminis Portal
  • Newsroom
    • Blog
    • Einstein in the News
    • Expert List for Media
    • Features
    • Magazine
    • Multimedia
    • News Releases
    • Research Briefs
    • Social Media Hub
  • Policies
    Research
    • Collaboration Zone
    • Scientific Resources
    Video
    Visitors
    • Campus Map
    • Directions
    Webmail
ALBERT EINSTEIN ®
College of Medicine
© Albert Einstein College of Medicine | Privacy Policy | Terms of Use | Webmaster
Click here to log in