Sironi J, Aranda A, Nordstrøm L, and Schwartz EL. Lysosome membrane permeabilization and disruption of mTOR-lysosome interaction are associated with the inhibition of lung cancer cell proliferation by a chloroquinoline analog. Molecular Pharmacology, 2019; 95:127-138.
Cheng H, Zou Y, Ross JS, Wang K, Liu X, Halmos B, Ali SM, Liu H, Verma A, Montagna C, Chachoua A, Goel S, Schwartz EL, Zhu C, Shan J, Yu Y, Gritsman K, Yelensky R, Lipson D, Otto G, Hawryluk M, Stephens PJ, Miller VA, Piperdi B, Perez-Soler R. RICTOR amplification defines a novel subset of lung cancer patients who may benefit from treatment with mTOR1/2 inhibitors. Cancer Discovery, 2015; 5:1262-70.
Nordstrøm LU, Sironi J, Aranda E, Maisonet J, Perez-Soler J, Wu P and Schwartz EL. Discovery of autophagy inhibitors with antiproliferative activity in lung and pancreatic cancer cells. ACS Medicinal Chem. Letters 2015; 6:134-9.
Zou Y, Ling YH, Sironi, J, Schwartz EL, Perez-Soler R, Piperdi B. (2013) The autophagy inhibitor chloroquine overcomes the innate resistance to erlotinib of non-small cell lung cancer cells with wild-type EGFR. J. Thoracic Oncology, 8:693-702.
Pula G, Dunn WB, Garonna E, Watson KE, Hirano M, Pizzorno G, Schwartz EL, el Kouni MH, Wheeler-Jones CPD. (2010) Paracrine stimulation of endothelial cell motility and in vitro wound repair by platelet-derived deoxyribose-1-phosphate. Arteriosclerosis, Thrombosis, and Vascular Biology. 30:2631-8.
Lu H, Klein RS and Schwartz EL (2009) Anti-angiogenic and anti-tumor activity of a novel thymidine phosphorylase inhibitor, 6-(2-aminoethyl)amino-5-chlorouracil (AEAC), in combination with the VEGF-Trap. Clinical Cancer Research, 15: 5136-5144.
Schwartz EL (2009) Anti-vascular actions of microtubule-binding drugs. Clinical Cancer Research 15:2594-2601.
Murtagh J, Lu H and Schwartz EL (2006) Taxotere-induced inhibition of endothelial cell migration is a result of Hsp90 degradation. Cancer Research 66:8192-8199.
Lu, H, Murtagh J and Schwartz EL (2006) The microtubule binding drug laulimalide inhibits VEGF-induced human endothelial cell migration, and is synergistic when combined with Taxotere. Molecular Pharmacology 69:1207-1215.
Hotchkiss, KA, Ashton AW and Schwartz EL (2003) The angiogenic factors thymidine phosphorylase and 2-deoxyribose stimulate human endothelial cell migration by activation of integrins alpha-5 beta-1 and alpha-v beta-3. J. Biological Chemistry 278:19272-19279.