Xu C, Gao X, Wei Q, Nakahara F, Zimmerman SE, Mar J, Frenette PS. Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow. Nat Commun. 2018 Jun 22;9(1):2449.
Maryanovich M, Zahalka AH, Pierce H, Pinho S, Nakahara F, Asada N, Wei Q, Wang X, Ciero P, Xu J, Leftin A, Frenette PS. Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. Nat Med. 2018 May 7. doi: 10.1038/s41591-018-0030-x.
Pinho S, Marchand T, Yang E, Wei Q, Nerlov C, Frenette PS. Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches. Dev Cell. 2018 Mar 12;44(5):634-641.
Zahalka AH, Arnal-Estapé A, Maryanovich M, Nakahara F, Cruz CD, Finley LWS, Frenette PS. Adrenergic nerves activate an angio-metabolic switch in prostate cancer. Science. 2017 Oct 20;358(6361):321-326.
Pierce H, Zhang D, Magnon C, Lucas D, Christin JR, Huggins M, Schwartz GJ, Frenette PS. Cholinergic Signals from the CNS Regulate G-CSF-Mediated HSC Mobilization from Bone Marrow via a Glucocorticoid Signaling Relay. Cell Stem Cell. 2017 May 4;20(5):648-658.
Asada N, Kunisaki Y, Pierce H, Wang Z, Fernandez NF, Birbrair A, Ma'ayan A, Frenette PS. Differential cytokine contributions of perivascular haematopoietic stem cell niches. Nat Cell Biol. 2017 Mar;19(3):214-223.
Khan JA, Mendelson A, Kunisaki Y, Birbrair A, Kou Y, Arnal-Estapé A, Pinho S, Ciero P, Nakahara F, Ma'ayan A, Bergman A, Merad M, Frenette PS. Fetal liver hematopoietic stem cell niches associate with portal vessels. Science. 2016 Jan 8;351(6269):176-80.
Zhang D, Chen G, Manwani D, Mortha A, Xu C, Faith JJ, Burk RD, Kunisaki Y, Jang JE, Scheiermann C, Merad M, Frenette PS.Neutrophil ageing is regulated by the microbiome. Nature. 2015 Sep 24;525(7570):528-32.
Bruns I, Lucas D, Pinho S, Ahmed J, Lambert MP, Kunisaki Y, Scheiermann C, Schiff L, Poncz M, Bergman A, Frenette PS. Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion. Nat Med. 2014 Nov;20(11):1315-20
Hanoun M, Zhang D, Mizoguchi T, Pinho S, Pierce H, Kunisaki Y, Lacombe J, Armstrong SA, Dührsen U, Frenette PS. Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche. Cell Stem Cell. 2014 Sep 4;15(3):365-75.
Mizoguchi T, Pinho S, Ahmed J, Kunisaki Y, Hanoun M, Mendelson A, Ono N, Kronenberg HM, Frenette PS. Osterix marks distinct waves of primitive and definitive stromal progenitors during bone marrow development. Dev Cell. 2014 May 12;29(3):340-9.
Kunisaki Y, Bruns I. Scheiermann C, Pinho, S, Ahmed J, Zhang D, Mizoguchi M, Wei Q, Lucas D, Ito K, Mar JC, Bergman A. and Frenette PS. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature. 2013. Oct 31;502(7473):637-43.
Magnon C, Hall SJ, Lin J, Xue X, Gerber L, Freedland SJ, and Frenette PS. Autonomic tumor nerve development contributes to prostate cancer progression. Science. 2013. Jul 12;341(6142):1236361.
Lucas D, Scheiermann C, Chow A, Kunisaki Y, Bruns I, Barrick C, Tessarollo L and Frenette PS., Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration. Nature Med. 2013 Jun;19(6): 695-703.
Chow A, Huggins M, Ahmed J, Hashimoto D, Lucas, D, Kunisaki Y, Pihno S, Leboeuf M, Noizat C, van RooijenN, TanakaM, Zhao ZJ, Bergman A, Merad M, and Frenette PS. CD169+ macrophages provide a niche promoting erythropoiesis under homeostasis and stress. Nature Med. 2013 Apr;19(4):429-36.
Méndez-Ferrer S, Michurina T, Ferraro F, Mazloom AR, MacArthur BD, Lira SA, Scadden DT, Maayan A, Enikolopov GN, and Frenette PS. Mesenchymal and hematopoietic stem cells form a unique bone marrow niche. Nature. 2010 Aug 12;466(7308):829-34.
Hidalgo A, Chang J, Jang JE, Peired AJ, Chiang EY and Frenette PS. Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury. Nature Med. 2009 Apr;15(4):384-91.
Méndez-Ferrer S, Lucas D, Battista M, and Frenette PS. Haematopoietic stem cell release is regulated by circadian oscillations. Nature 2008 Mar 27;452(7186):442-447.
Katayama Y, Battista M, Kao WM, Hidalgo A, Thomas SA and Frenette PS. Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell. 2006 Jan 27;124(2):407-21.