Dr. Thompson's research addresses racial and ethnic disparities in cancer health outcomes and healthcare participation in general. She is the principal investigator of grants funded by Susan G. Komen for the Cure and the DOD Breast Cancer research program to develop and evaluate interventions to promote post-treatment healthcare among African American breast cancer survivors. Both studies involve training peer-lay health workers as interventionists and educators. Dr. Thompson was also recently co-investigator of two funded studies to test the efficacy of a culturally targeted genetic counseling protocols and a computer- based decision genetic testing decision aid. Dr. Thompson was also a recent PI of a study examining prostate cancer educational materials designed for African American men. She is currently a co-investigator on an NCI-funded study of patient navigation for colorectal cancer screening. Her other research includes investigation of medical mistrust among African American and Latino adults and communication within healthcare-related interactions.